Erhaltungstherapie mit Methadontabletten - Eine Übersicht
Erhaltungstherapie mit Methadontabletten - Eine Übersicht
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Methadone is contraindicated rein patients with a known hypersensitivity to methadone hydrochloride or any other ingredient in methadone hydrochloride tablets.
Several factors complicate the Ausdeutung of investigations of the children of women Weltgesundheitsorganisation take methadone during pregnancy. These include the maternal use of illicit drugs, other maternal factors such as nutrition, infection, and psychosocial circumstances, limited information regarding dose and duration of methadone use during pregnancy, and the fact that most maternal exposure appears to occur after the first trimester of pregnancy. In addition, reported studies generally compare the benefit of methadone to the risk of untreated addiction to illicit drugs; the relevance of these findings to pain patients prescribed methadone during pregnancy is unclear.
Pharmacodynamic interactions may occur with concomitant use of methadone and potentially arrhythmogenic agents such as class I and III antiarrhythmics, some neuroleptics and tricyclic antidepressants, and calcium channel blockers.
Rein patients being treated for opioid dependence, this should include weighing the risk of methadone against the risk of maternal illicit drug use.
Rein the selection of an initial dose of methadone hydrochloride tablets, attention should Beryllium given to the following:
Methadone treatment for analgesic therapy rein patients with acute or chronic pain should only be initiated if the potential analgesic or palliative care benefit of treatment with methadone has been considered to outweigh the risk of QT prolongation that has been reported with high doses of methadone.
Methadone belongs to a class of drugs called opioids (narcotics). A class of drugs is a group of medications that work rein a similar way. These drugs are often used to treat similar conditions.
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However, if the use of methadone is necessary hinein such patients, a sensitivity test should Beryllium performed rein which repeated small, incremental doses of methadone are administered over the course of several hours while the patient's condition and vital signs are under careful observation.
The intensity of the syndrome does not always correlate with the maternal dose or the duration of maternal exposure. The duration of the withdrawal signs may vary from a few days to weeks or even months. There is no consensus on the appropriate management of infant withdrawal.
Infants born to mothers physically dependent on opioids may also be physically dependent and may exhibit respiratory difficulties and withdrawal symptoms (Weiher PRECAUTIONS, Pregnancy, Laboratorium and Delivery).
Patients seeking to Methadontabletten online kaufen discontinue methadone maintenance treatment of opioid dependence should Beryllium apprised of the high risk of relapse to illicit drug use associated with discontinuation of methadone maintenance treatment.
Respiratory depression is the chief hazard associated with methadone hydrochloride administration. Methadone's peak respiratory depressant effects typically occur later, and persist longer than its peak analgesic effects, particularly rein the early dosing period.